Antimicrobial

Mouth dissolving films is a new drug delivery system for oral route. This delivery system consists of a very thin oral strip, which is simply placed on the patients tongue or any oral mucosal tissue, instantly wet by saliva, film rapidly hydrates and then disintegrates and/or dissolve to release the medication. In the formulation of oral film, the most important ingredient is polymer which helps in film formation. Mainly hydrophilic polymers are used in mouth dissolving films.

Chlorine dioxide is generated from aqueous liquids container alkali metal or alkaline earth metal chlorites, and compounds which liberate chlorine in water. Dry, stable, solid compositions, in one or two parts, can be made from these and other ingredients.

The compound chlorine dioxide (ClO2), now commercially important, is not in fact a recent discovery. The gas was first produced by Humphrey Davy in 1811 when reacting hydrochloric acid with potassium chlorate. This yielded "euchlorine", as it was then termed. Watt and Burgess, who invented alkaline pulp bleaching in 1834, mentioned euchlorine as a bleaching agent in their first patent. Chlorine dioxide then became well known as a bleach and later a disinfectant.

The U.S. Environmental Protection Agency’s (EPA) National Homeland Security Research Center (NHSRC) Technology Testing and Evaluation Program (TTEP) helps to protect human health and the environment from adverse impacts of terrorist acts by carrying out performance tests on homeland security technologies. TTEP recently evaluated the performance of liquid and foam decontamination technologies under vendor-specified application conditions to decontaminate test coupons prepared from the materials listed below.

Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.

This study reports the effect of exposure to liquid carbon dioxide on the mechanical properties of selected medical polymers. The tensile strengths and moduli of fourteen polymers are reported. Materials were exposed to liquid CO2, or CO2 + trace amounts of aqueous H2O2, at 6.5 MPa and ambient temperature. Carbon dioxide uptake, swelling, and distortion were observed for the more amorphous polymers while polymers with higher crystallinity showed little effect from CO2 exposure.

A multi-layer, biodegradable film is disclosed. The multi-layer, biodegradable film contains a biodegradable core layer and a biodegradable pressure sensitive adhesive layer. The film may further contain a biodegradable, printable layer and a release liner.

An adhesive composition includes a polymerizable adhesive monomer and at least one dual finction stabilizer. The stabilizer provides superior stabilization and shelf-life of the composition, and enhances wound healing properties of the monomer composition.

A method of treating or preventing tinea cruris, commonly known as Jock Itch, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to tinea cruris, optionally with at least one of an additional anti-fungal agent or a skin care additive, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.

A method of treating insect bites includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with an insect bite, optionally with at least one of an additional active agent, and allowing the polymerizable monomer composition to polymerize to form a polymer film over the area of skin.