Technical documentation

An adhesive composition (I) comprises up to 50 wt.% monomeric 2-alkoxy-alkyl-2-cyanoacrylate and 1-15 wt.% poly(1-5C) alkyl(meth)acrylate having an average mol. wt. of 10,000-60,000. An adhesive composition (I) comprises(with respect to components (A)-(C)): (a) up to 50 wt.% monomeric 2-alkoxy-alkyl-2-cyanoacrylate; (b) 1-15 wt.% poly(1-5C) alkyl(meth)acrylate having an average mol. wt. of 10,000-60,000; (c) 0-10 wt.% hydrophobic pyrogenic silicic acid; (d) 50-10,000 ppm polymerization stabilizer and; (e) 200-10,000 ppm accelerator.

A process for enhancing the security of implantable surgical devices secured to bone tissue comprising implanting in bone tissue a surgical device with a biocompatible adhesive and/or sealant selected from the group consisting of: p1 (a) a material made from monomers of the formula:

The mechanical properties of the adhesively bonded joints with ethyl-2-cyanoacrylate and ethyl-2-cyanoacrylate modified with poly(methylmethacrylate) were determined. The modifier lowers tensile stiffness, increases deformability and relaxation of the adhesive bond and improves impact resistance. A morphological structure similar to an interpenetrating network system is suggested which arises from the rapid polymerization of the solvent. The results obtained may be helpful for the design of joints with cyanoacrylate bonding.

A cyanoacrylate adhesive composition thickened by a copolymer or terpolymer resin capable of being dissolved or solvated by the cyanoacrylate monomer exhibits significantly improved peel strength. Storage stability is also enhanced. Preferred thickeners are acrylonitrile-butadiene-styrene terpolymers, methacrylate-butadiene-styrene terpolymers, and vinylidene chloride-acrylonitrile copolymers. Preferred monomers are methyl and ethyl cyanoacrylates.