Technical documentation

A New Bioabsorbable Polymer: An Ideal Material for Medical Implants?

For more than 100 years, orthopedic surgeons have been repairing serious bone fractures by binding the fractures with screws, pins, and other fixation-type devices. Early on, these devices were often made from common metals such as iron or steel. Later on, they were made of highly sophisticated metal alloys of titanium, zirconium, niobium, and tantalum. Still the search continued for materials that would be more compatible with the human body, and that search led researchers to consider bioabsorbable polymers.

Synthesis of acrylate functional telechelic poly(lactic acid) oligomer by transesterification

By:

Polyester/Cyanoacrylate Tissue Adhesive Compositions

US7351426

By:

Shalaby W. Shalaby

M. Aaron Vaughn

This invention addresses absorbable cyanoacrylate-based tissue adhesive compositions based primarily on an alkoxy cyanoacrylate combined with one or more alkyl cyanoacrylate(s), a stabilizer against premature anionic polymerization, and/or an absorbable polymeric modifier with improved, and preferably, functional properties for use, primarily, for internal wound repair applications.

A Review of Block Polymer Surfactants

By:

Irving R. Schmolka

A brief historical review of four series of commercially available block polymer surface-active agents—the PLURONICR, TETRONICR, PLURADOTR, and PLURONICR R polyols—is presented. A comparison is made of the physical properties within each series, in the form of trend lines. These parameters encompass solubility, rate of solubility, wetting, foaming, defoaming, emulsification, thickening, cleansing, and toxicity.

Cyanoacrylate Compositions comprising a Soluble Antimicrobial Agent

WO0035276

By:

Carlos R. Morales

Eric J. Sterling

Shane C. Karnik

Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film of mammalian skin.

Stabilized Cyanoacrylate Adhesives containing Bis-Trialkylsilyl Esters of Sulfuric Acid

US4650826

By:

Helmut Waniczek

Wilfried Kniege

This invention relates to stabilized adhesives, to which silyl esters are added for stabilization.

Process for the Preaparation of Iodine-Polyvinylpyrrolidone by Dry Mixing

US2706701

By:

Hans Beller

This invention relates to an improved for preparing a dry powdered adduct of iodine and polymeric 1-vinyl-2-pyrrolidone (hereinafter called polyvinylpyrrolidone) whereby a stable composition is formed which is readily available and germicidally and bactericidally active form which is essentially non-toxic to warm-blooded animals.

Povidone Iodine -Revisited

By:

Povidone Iodine or polyvinyl pyrrolidone-iodine, commonly abbreviated as PVP-I was discovered by American scientists H. A. Shelanski and M. V. Shelanski. PVP- I was introduced to the pharmaceutical market as an antiseptic agent in the 1950’s and is found to be more effective than other iodine formulations and was less toxic

Preparation of Iodine Polyvinyl-Pyrrolidone Adducts

US2900305

By:

Sidney Siggia

This invention relates to the preparation of an adduct of iodine and polymeric 1-vinyl-2-pyrrolidone (hereinafter referred to as polyvinylpyrrolidone) whereby there is fomred a composition which is readily soluble in water to form a stable solution and which provides iodine in readily available germicidally and bactericidally active form which is essentially non-toxic to warm-blooded animals.

Process of Stabilizing Polyvinyl Pyrrolidone-Iodine Compositions

US2826532

By:

William A. Hosmer

This invention relates to a process of stabilizing a dry powered adduct of iodine and polymeric 1-vinyl-2-pyrrolidone (hereinafter referred to as polyvinyl pyrrolidone) whereby a stable composition is obtained which when dissolved in water will not change its pH and maintain a constant available iodine content.

Search Docs