Polyester/Cyanoacrylate Tissue Adhesive Compositions
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This invention addresses absorbable cyanoacrylate-based tissue adhesive compositions based primarily on an alkoxy cyanoacrylate combined with one or more alkyl cyanoacrylate(s), a stabilizer against premature anionic polymerization, and/or an absorbable polymeric modifier with improved, and preferably, functional properties for use, primarily, for internal wound repair applications.
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United States Patent
US007351426B2
(12) (10) Patent No.: US 7,351,426 B2
Shalaby et al. (45) Date of Patent: Apr. 1, 2008
(54) POLYESTER/CYANOACRYLATE TISSUE 3,223,083 A 12/1965 Cobey ....................... .. 128/92
ADHESIVE COMPOSITIONS 3,264,249 A 8/1966 Araki et al. ............. .. 260/32.4
3,559,652 A 2/1971 Benitt ...................... .. 128/334
(75) IHVBIHOFSI Sha1abyW- Sha1aby,AI1derS0I1, SC 4,105,594 A * 8/1978 Dieterich etal. .. 521/100
(US); M- Aaron Vaughn: Easleys SC 5,350,798 A 9/1994 Linden et al. . . . . . . . . .. 525/41
(US) 5,422,068 A 6/1995 Shalaby etal. 422/22
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