Bioabsorbables Cyanoacrylate Tissue Adhesives
Year:
Abstract:
Bioabsorbable cyanoacrylate-based tissue adhesives containing bioabsorbable copolymers are disclosed. The copolymers are preferably derived from .epsilon.-caprolactone, lactide and glycolide monomers or from butyl 2-cyanoacrylate, glycolide, lactide, .epsilon.-caprolactone monomers. The adhesives are characterized by increased biodegradability, increased viscosity and increased flexibility. The adhesives are useful for wound and incision closure, and for medical devices, including implants.
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Language:
US006224622B1
(12) United States Patent (10) Patent No.2 US 6,224,622 B1
Kotzev (45) Date of Patent: May 1, 2001
(54) BIOABSORABLE CYANOACRYLATE TISSUE 6,001,345 * 11/1999 Askilletal. .................... .. 424/78.25
ADHESIVES 6,093,780 * 7/2000 Attarwala ........................... .. 526/298
(75) Inventor: Dimiter Lubomirov Kotzev, * Cited by examiner
Alpharetta, GA (US)
(73) Assignee: Chemence, Inc., Alpharetta, GA (US) Primary Examme,,_MiChae1 H. Thaler
Assistant Examiner—(Vil
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