2000

A composition comprising of a monomer component comprised of an alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment.

Polyalkyl 2-cyanoacrylates begin to retropolymerize and deteriorate dramatically at temperatures above 80°C. They bond rapidly to the metal surfaces and readily lose strength even at ambient temperatures. These two drawbacks of the cyanoacrylates have made this class of adhesives unpopular as structural adhesives. Several attempts have been made to increase the thermal stability and the stability of the bond between the metal surfaces by adding chemicals like cyclopentadienoates and anhydrides to the cyanoacrylates.

A brief review is given about the development of rubber isostatic pressing (RIP) of powders for magnets and other materials that includes: principles of RIP; RIP apparatuses; recent progress; and advantages of RIP. As the recent progress, a new filling technique, ‘air tapping (AT) and grid separation (GS)’, is presented.

New sintered Nd-Fe-B near net-shape magnets with a high remanent polarization of 1.47 T, a coercivity HcJ of 9.6 kA/cm (12 kOe) and a maximum energy density of 420 kJ/m3 (53 MGOe) can be manufactured by rubber isostatic pressing. The optimization of the remanent polarization by an improved alignment process of the powder particles results in a decrease of the coercivity by 0.4 kA/cm per 1 % ∆fφ for alignment coefficients fφ in the range 96 to 98 %. For alignment coefficients between 98 to 99 % the decrease of the coercivity even increases to about –1 kA/cm per % 1 ∆fφ.

Supercritical carbon dioxide (SC CO2) was used as an aid in fabricating polymer/polymer composites. Using a two-stage process, ethyl 2-cyanoacrylate (ECA) monomer was anionically polymerized within poly(tetrafluoroethylene-co-hexafluoropropylene) substrates. The composite fabrication process involved first infusing triphenylphosphine (the initiator) into the substrate using SC CO2. In the second step, monomer was introduced (again using SC CO2) to the substrate. As the monomer absorbed into the initiator-containing substrate, it polymerized.

Supercritical carbon dioxide (SC CO2) was used as an aid in fabricating polymer/polymer composites. Using a two-stage process, ethyl 2-cyanoacrylate (ECA) monomer was anionically polymerized within poly(tetrafluoroethylene-co-hexafluoropropylene) substrates. The composite fabrication process involved first infusing triphenylphosphine (the initiator) into the substrate using SC CO2. In the second step, monomer was introduced (again using SC CO2) to the substrate. As the monomer absorbed into the initiator-containing substrate, it polymerized.

A method is provided for sterilizing materials, particularly polymers, for drug delivery and implantation, wherein the material is treated with supercritical fluid carbon dioxide at pressures in the range of 2000 to 3000 psi (140 to 210 bar) and temperatures preferably between 30 and 45.degree. C. for periods between 20 minutes and six hours, more preferably between 0.5 and 2 hours.

Methods and compositions for closing and sealing a wound, laceration, incision, or other percutaneous opening using an adhesive. In one preferred embodiment, the sides of the percutaneous opening are brought together in apposition and the adhesive is applied to the opening and the skin immediately adjacent thereto. Adhesives used in the methods exhibit sufficient viscosity to substantially prevent flow of the adhesive into the percutaneous opening. In a preferred embodiment, the adhesive is a sealing medium comprising an adhesive component and a microparticulate component.

A biocompatible monomer composition includes at least one monomer, which forms a medically acceptable polymer, and an effective amount of at least one heat dissipating agent sufficient to reduce exothermic polymerization temperature increase of the composition. The heat dissipating agent enhances patient comfort and prevents necrosis of living tissue normally encountered with such medical adhesives.