1979

Adhesive compositions having enhanced bond strength are obtained by mixing a monomeric ester of 2-cyanoacrylic acid with an anionic polymerization inhibitor and from 1 to 30 mmoles per kg. of adhesive of an adhesion promoter of the formula: wherein R' is hydrogen or an alkyl, aryl or cycloalkyl group having 1-10 carbon atoms. Such compositions may be used on a wide variety of substrates and are particularly useful on metals.

Le sulfate de bis (triméthylsilyle) composé aisément accessible, permet d'introduire le groupe sulfonique dans des dérivés fonctionnels tels que les éthers aromatiques, les chlorures et anhydrides d'acides aliphatiques, sans qu'il y ait de modifications notables de la fonction considerée. Dans le cas d'in chlorure d'acide alpha-chloré, on observe cependant une disulfonation accompagnée de decarboxylation.

An adhesive composition comprising monomeric methyl allyl methylenemalonate is useful for bonding together a wide range of materials.

A fast-setting .alpha.-cyanoacrylate-type adhesive composition having good storage stability comprising an .alpha.-cyanoacrylate and about 0.1 ppm or more of at least one macrocyclic polyether compound or an analogue thereof, such as 18-crown-6 or 15-crown-5.

An adhesive composition comprising an .alpha.-cyanoacrylate and about 0.0001% by weight to about 20% by weight, based on the weight of the adhesive composition, of at least one compound selected from the group consisting of (1) polyehtylene glycols having a degree of polymerization of at least 3, and (2) non-ionic surface active agents having a poly(ehtyleneoxy) moiety therein with the poly(ehtyleneoxy) moiety having a degree of polymerization of at least 3.

Ocular tolerance to cyanoacrylate tissue adhesives was evaluated in rabbits. In the experimental studies, tissue adhesives were implanted intralamellarly, subconjunctivally, and in the anterior chamber. The eyes were examined clinically and histologically at different time intervals. In the cornea and conjunctiva, the adhesive reacted as any inert material. The reaction was considerably less than that to silk or catgut. In the anterior chamber, the reaction was moderate in most cases.