This research defined and evaluated mechanical properties of prototypes created using a plaster based three-dimensional printing (3DP) system commercialized by Z Corporation. 3DP is one of the fastest growing forms of rapid prototyping. Till date, there is little or no information available on material properties of infiltrants used in 3DP. This research work evaluated and documented some of the useful information for 3DP users by determining the effect of build position, build orientation and infiltration materials on the strength of prototypes.