The effect of adding various anhydrides, such as succinic, maleic, phthalic, and pyromellitic anhydrides, to alkyl cyanoacrylate on the heat ageing and moisture resistance properties of the adhesive bonds is studied. Such an addition was generally found to improve the adhesion of alkyl cyanoacrylate to metals, in addition to providing other improvements. Maleic anhydride is the only one that appears to act as a crosslinking agent with cyanoacrylate, thus providing improved heat and moisture-resistant bonds.
A process for bonding a polyolefin, polyfluoroolefin, polyethylene terephthalate, polyacetal, nylon or plasticizer-rich soft polyvinyl chloride substrate to a like substrate or for bonding a polyolefin, polyfluoroolefin, polyethylene terephthalate, polyacetal, nylon or plasticizer-rich soft polyvinyl chloride substrates to another substrate which comprises applying to the surface of at least one of the substrates to be bonded together an adhesion promoter composition comprising 0.001-10 wt.
Solubility of CO2 and N2O in Twelve Solvents, 18° to 36° C.-Since according to the Lewis-Langmuir theory these two gases have similar molecular structures, it is of interest to compare their solubilities in various liquids. In the method adopted, the air was thoroughly removed from the solvent by boiling and then the gas to be tested, having been carefully purified with the help of liquid air, was admitted and shaken up with the solvent until no further solution took place. Observations accurate to better than one per cent.
Cyanoacrylate polymer foams can be obtained by blending cyanoacrylate monomer with an appropriate solvent and a polymerization initiator. Foaming takes place in seconds at room temperature. Various monomers, solvents and initiators were tested and best performance compositions and ratios were determined. The resultant foams are lightweight and can occupy volume up to 30 times that of the original cyanoacrylate monomer. The onset time and temperature of foaming can be regulated in wide ranges. Odourless foaming compositions were obtained.
Polycyanoacrylate foam is made by mixing together a cyanoacrylate monomer, a liquid foaming agent and a polymerisation initiator. The mixture simultaneously polymerises and foams. The foaming agent is usually an organic compound with a boiling point not higher than 100 °C, miscible with the monomer but not a solvent for the polymer. The monomer may be any 2-cyanoacrylate ester compatible with the composition.
The efficacy of primaquine-loaded polyisohexylcyanoacrylate (PIHCA) nanoparticles was evaluated using J774G8 macrophage-like cells infected with Leishmania donovani: as an in vitro model of visceral leishmaniasis. The in vitro antileishmanial activity of primaquine-loaded nanoparticles showed a 21-fold increase in ED50 compared with free primaquine. Although unloaded PIHCA nanoparticles also exhibited a significant anti-leishmanial effect, the loaded nanoparticles showed a synergistic effect compared with a mixture of unloaded nanoparticles and free primaquine at equivalent concentrations.
The biocompatibility and bioresorption of 3-methoxybutylcyanoacrylate (MBCA) was evaluated in vivo using female Wistar albino rats. MBCA was found to elicit slight to moderate tissue reaction similar to isobutylcyanoacrylate (iBCA) which has been sold commercially as a surgical adhesive (Bucrylate®, Ethicon). MBCA was judged less reactive to tissue than ethylcyanoacrylate (ECA). The MBCA implants in rat gluteal muscles also resorbed within approx. 16 wk while iBCA implants remained essentially unchanged at 36 wk in vivo.
